Tisch
PVDF Syringe Filters, 0.45um, 25mm, Double Luer Lock, PP Housing, Sterile, 100/Pk SKU: SPEC18213

Polyvinylidene Fluoride (PVDF) Syringe Filters - SPEC18213

Processing analytical samples across diverse organic solvents creates constant challenges when membranes degrade mid-filtration, compromising sample integrity and forcing you to restart your preparation workflows. Advanced hydrophobic PVDF membrane technology delivers exceptional chemical resistance across aggressive solvent systems where conventional materials fail. Sterile 0.45µm construction with validated 4.35psi bubble point and polypropylene housing provides contamination-free clarification for HPLC mobile phases, organic extracts, and chemical formulations requiring particle removal without bacterial retention claims.

Key PVDF Membrane Characteristics

• Hydrophobic membrane design requires alcohol pre-wetting before aqueous sample processing, ensuring complete membrane activation and consistent flow characteristics throughout your filtration operations
• Exceptional chemical stability withstands acetonitrile, methanol, chlorinated solvents, and aggressive organic mobile phases that rapidly degrade cellulosic and nylon membrane alternatives
• 0.45µm pore size removes particulates and protects analytical columns from fouling, providing clarification for chromatography applications without sterile-grade bacterial retention capabilities
• Ultra-low protein binding characteristics preserve analyte concentrations in biological samples, preventing adsorptive losses that compromise quantitation accuracy in your analytical workflows
• Broad temperature tolerance up to 80°C accommodates warm sample processing requirements while maintaining membrane integrity throughout demanding laboratory operations

Key Construction Characteristics

• Polypropylene housing delivers chemical compatibility with aggressive organic solvents while withstanding elevated temperatures, supporting diverse analytical sample preparation protocols
• Double luer lock connection provides secure, leak-proof attachment to syringes and transfer lines, preventing disconnection during manual and automated filtration operations
• 72.5psi maximum operating pressure supports both manual syringe filtration and integration with low-pressure pumping systems for higher-throughput sample processing
• Sterile gamma-irradiated packaging eliminates bioburden concerns in contamination-sensitive applications, delivering ready-to-use clarification without requiring pre-use sterilization procedures

When your analytical workflows demand clarification across diverse solvent systems from polar buffers to nonpolar organics, membrane chemical resistance determines processing success. PVDF's exceptional solvent stability handles the complete spectrum your laboratory encounters daily. Sterile individually-wrapped filters maintain your contamination control protocols while delivering the chemical resistance and low protein binding that preserve sample integrity, protect expensive analytical instrumentation, and ensure reliable results across demanding chromatography and analytical applications.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

4.35psi

Burst Pressure (psi)

116psi

Connection Type

Double Luer Lock

Construction

Polypropylene (PP)

Diameter

25mm

Dimensions (W x D x H)

21.8mmx28.6mm

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

72.5psi

Maximum Operating Temperature (°C)

80℃

Pack Count

100

Pore Size (µm)

0.45

Sterility

Sterile

Weight

0.70

Wetability

Hydrophobic

• HPLC Mobile Phase Clarification — Remove particulates from organic and aqueous mobile phases before injection, protecting columns and extending service life
• Organic Solvent Filtration — Process acetonitrile, methanol, and chlorinated solvents for analytical applications where chemical compatibility prevents degradation
• LC-MS Sample Preparation — Clarify biological extracts and chemical standards before mass spectrometry, protecting ionization sources from particulate contamination
• Chemical Formulation Processing — Filter pharmaceutical intermediates and specialty chemical solutions where solvent resistance maintains membrane integrity
• Environmental Sample Preparation — Clarify organic extracts from soil and water samples, removing suspended solids that interfere with chromatographic analysis
• Quality Control Testing — Prepare samples for routine analytical testing where sterile packaging eliminates contamination risks in controlled laboratory environments