Tisch
PTFE Syringe Filters, Hydrophilic, 0.1um, 33mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF18080

Polytetrafluoroethylene (PTFE) Syringe Filters - SF18080

Featuring hydrophilic PTFE membrane technology with integrated glass fiber prefilter engineered for mycoplasma removal in high-volume biological processing. Advanced dual-layer architecture combines 0.1µm absolute retention with high-capacity particulate protection for challenging samples containing cellular debris. Modified fluoropolymer surface eliminates pre-wetting requirements, enabling immediate filtration of aqueous biologics while maintaining exceptional chemical compatibility. Polypropylene housing construction withstands pressures up to 87psi while supporting extended processing campaigns.

Key Hydrophilic PTFE Membrane Characteristics

• Absolute 0.1µm mycoplasma retention validated through industry-standard challenge testing with Acholeplasma laidlawii organisms
• Hydrophilic surface technology enables spontaneous wetting with aqueous solutions, eliminating alcohol pre-treatment protocols
• Low protein binding platform preserves therapeutic biologics and proteins through minimal surface adsorption during filtration
• Broad chemical compatibility resists degradation from analytical solvents, buffers, and biological process chemicals
• Membrane thickness of 80-140µm balances structural integrity with efficient 12ml flow rate performance

Key Construction Characteristics

• Glass fiber prefilter extends primary membrane operational life by removing high debris loads before submicron stage
• Large 33mm diameter provides 4.6cm² filtration area supporting processing volumes up to 110ml capacity
• Low 100µL holdup volume minimizes sample loss while maintaining high-volume processing efficiency
• Luer-Lok/Luer Slip dual interface ensures secure connection compatibility with all standard laboratory syringes

SF18080 filters deliver validated mycoplasma removal for demanding biotechnology and pharmaceutical workflows. The integrated prefilter protects the 0.1µm membrane from premature fouling, extending operational life when processing cell culture harvests and fermentation broths. Your laboratory achieves consistent submicron retention while the hydrophilic surface maintains rapid flow rates through aqueous biological matrices.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

87psi.

Connection Type

Luer-Lok/Luer Slip

Construction

PP

Diameter

33mm

Filtration Area

4.6cm²

Flow Rate

12ml

Holdup Volume

100μL

Incompatibility

Bases, esters, ethers, ketones

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-140μm

Pack Count

100

Pore Size (µm)

0.1

Prefilter (Yes/No)

Yes

Prefilter Material

GF

Sterility

NonSterile

Sterilization

Autoclave 121°C for 30min/ Gamma 25kGy

Volume Throughput (ml)

110ml

Weight

0.96

Wetability

Hydrophilic

• Cell Culture Processing - Removes mycoplasma from fermentation broths and harvest streams containing particulate loads for sterile processing
• Biotech Manufacturing - Filters large-volume biologics and vaccine intermediates requiring validated mycoplasma-free processing assurance
• Quality Control Testing - Processes bulk pharmaceutical samples for mycoplasma detection and sterility verification in cGMP operations
• Clinical Sample Prep - Filters biological specimens and therapeutic candidates for downstream analytical testing in research protocols
• Protein Purification - Clarifies and sterilizes protein solutions from expression systems while removing cellular debris and mycoplasma
• Vaccine Production - Provides mycoplasma removal for large-volume vaccine components in biological manufacturing process streams