Tisch
PTFE Syringe Filters, Hydrophilic, 0.1um, 33mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF18080

Polytetrafluoroethylene (PTFE) Syringe Filters - SF18080

Biotechnology manufacturing, pharmaceutical process development, and clinical research laboratories require precision mycoplasma removal solutions for high-volume samples where particulate protection and submicron retention are equally critical. Advanced laboratory capabilities demand membrane technology that delivers validated 0.1μm mycoplasma retention while managing challenging biological matrices containing high debris loads. Engineered with expanded 33mm architecture combining hydrophilic PTFE membrane chemistry with integrated glass fiber prefilter, this filtration system provides comprehensive protection through dual-layer filtration architecture. Design optimization includes 29psi bubble point validation ensuring absolute 0.1μm retention, 4.9cm² high-capacity filtration area, and 100μL holdup volume supporting 110ml throughput capacity for demanding large-volume sterile processing workflows requiring extended membrane operational life.

Key PTFE Membrane Characteristics

• Absolute 0.1μm Mycoplasma Retention - Delivers complete removal of mycoplasma organisms and submicron particles with 29psi bubble point verification
• Hydrophilic Surface Technology - Modified fluoropolymer eliminates pre-wetting protocols, enabling immediate processing of aqueous biological samples
• Broad Chemical Compatibility - Resists degradation from analytical solvents and process chemicals while providing incompatibility documentation
• Low Protein Binding Platform - Preserves proteins and therapeutic biologics through minimal surface adsorption during filtration processes
• Validated Membrane Thickness - 80-140μm engineered depth ensures structural integrity while maintaining 12ml flow rate efficiency

Key Construction Characteristics

• 100μL Holdup Volume - Minimizes loss through optimized dead space design, balancing sample recovery with high-volume processing efficiency
• High-Capacity 33mm Platform - 4.9cm² effective area enables processing of large biological sample volumes up to 110ml capacity
• Glass Fiber Prefilter Integration - Extends primary membrane life through high-capacity particulate removal before the submicron filtration stage
• Universal Dual Luer System - Luer-Lok/Luer Slip interface ensures secure connection with all standard laboratory syringe configurations

Built for your demanding high-volume mycoplasma removal requirements, this hydrophilic PTFE system delivers structural integrity through 87psi operational ratings while maintaining validated submicron retention capabilities. Your laboratory achieves extended processing campaigns through glass fiber prefilter protection and maximum throughput with 110ml capacity, while the robust dual-layer construction ensures consistent performance across challenging biological matrices and debris-laden samples requiring absolute mycoplasma-free assurance.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

87psi.

Connection Type

Luer-Lok/ Luer Slip

Construction

PP

Diameter

33mm

Filtration Area

4.9cm²

Flow Rate

12ml

Holdup Volume

100μL

Incompatibility

Bases, esters, ethers, ketones

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-140μm

Pack Count

100

Pore Size (µm)

0.1

Prefilter (Yes/No)

Yes

Prefilter Material

GF

Sterility

NonSterile

Sterilization

Autoclave 121°C for 30min/ Gamma 25kGy

Volume Throughput (ml)

110ml

Wetability

Hydrophilic

• Cell Culture Harvest Processing - Removes mycoplasma from fermentation broths and cell culture harvests containing high particulate loads
• Biotechnology Process Development - Filters large-volume biologics and vaccine intermediates requiring mycoplasma-free processing assurance
• Pharmaceutical Quality Control - Processes bulk samples for mycoplasma testing and sterility verification in manufacturing operations
• Clinical Trial Sample Preparation - Filters biological specimens and therapeutic candidates for downstream analytical testing protocols
• Research Protein Purification - Clarifies and sterilizes protein solutions from expression systems containing cellular debris
• Vaccine Production Intermediates - Provides mycoplasma removal for large-volume vaccine components and biological manufacturing streams