Tisch
PVDF Syringe Filters w/ 3 Pre-Filters, 0.22 um, 25mm, Sterile, 100/Pk SKU: SF18308

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18308

Featuring 0.22 µm hydrophobic polyvinylidene fluoride membrane technology with a triple-layer prefilter system combining glass fiber and polypropylene stages delivering absolute bacterial retention, extended membrane lifetime through progressive particulate capture, and gamma-sterilized construction ensuring contamination-free processing across pharmaceutical manufacturing, analytical chemistry, and biotechnology applications requiring organic solvent compatibility. This combination ensures reliable sterile filtration. Additionally, 25mm diameter design with 100 µL holdup volume and 4.08 cm² filtration area supports standard-volume processing while triple prefilter protection maximizes throughput in challenging samples containing high particulate loads.

Key PVDF Membrane Characteristics

• Hydrophobic Membrane Architecture - Requires alcohol pre-wetting, enabling superior performance with organic solvents, aggressive chemicals, and non-aqueous mobile phases
• Exceptional Solvent Compatibility - Withstands acids, bases, alcohols, ketones, and harsh organic chemicals, maintaining membrane integrity throughout demanding applications
• 0.22 µm Absolute Bacterial Retention - Ensures sterile filtration performance, removing bacteria and submicron particles, protecting pharmaceutical product quality
• Minimal Protein Adsorption - Preserves sample concentration and biomolecule integrity through low-binding surface chemistry critical for biological preparations
• Outstanding Chemical Stability - Maintains compatibility across extreme pH ranges and concentrated chemical exposures, delivering consistent sterile filtration reliability

Key Construction Characteristics

• 100 µL Optimized Holdup Volume - Minimizes loss of valuable samples through controlled dead volume design, maximizing recovery in standard analytical workflows
• Polypropylene Housing with 60°C Rating - Delivers reliable thermal performance and chemical resistance throughout solvent processing and sterilization protocols
• Dual Luer-Lok/Luer Slip Connection - Supports versatile syringe attachment options, ensuring secure, leak-free operation with diverse laboratory equipment configurations
• Triple Prefilter System (GF+GF+PP) - Accelerates processing through progressive particulate capture, extending membrane lifetime and maintaining flow rates in high dirt-load samples

Designed for your most demanding sterile filtration applications where organic solvent compatibility and high particulate loads cannot compromise processing efficiency or absolute bacterial retention. The triple prefilter system prevents membrane fouling while hydrophobic PVDF membrane resists chemical degradation. Your laboratory achieves operational excellence through validated 0.22 µm sterile filtration, exceptional chemical resistance spanning acids and organic mobile phases, and triple-layer prefilter protection extending operational lifetime across pharmaceutical development, chromatography, and biotechnology workflows requiring both sterility and particulate management.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

14.5psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

20ml

Holdup Volume

100μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.22

Prefilter (Yes/No)

Yes

Prefilter Material

GF+GF+PP

Sterility

Sterile

Volume Throughput (ml)

50ml

Wetability

Hydrophobic

• HPLC Mobile Phase Sterilization - Removes bacteria from organic and aqueous mobile phases, protecting analytical columns and system integrity
• Pharmaceutical Injectable Production - Provides sterile filtration for drug formulations, ensuring patient safety through absolute microbial retention
• Organic Solvent Sample Sterilization - Processes aggressive chemicals requiring sterile conditions, maintaining chemical stability and contamination control
• Tissue Culture Media Filtration - Sterilizes nutrient solutions with high particulate content, preventing contamination in cell culture research
• API Solution Sterilization - Filters active pharmaceutical ingredients in organic solvents, ensuring sterile processing for drug manufacturing
• Analytical Reference Standard Preparation - Sterilizes calibration solutions with particulates, preventing microbial interference in testing protocols