Tisch
PVDF Syringe Filters w/ 3 Pre-Filters, 0.45 um, 25mm, 100/Pk SKU: SF18309

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18309

Laboratory professionals processing organic samples with high particulate content encounter premature membrane fouling and reduced throughput when clarification systems lack adequate prefilter protection, compromising both processing efficiency and solvent compatibility in analytical workflows requiring aggressive chemical resistance. Advanced 0.45 µm hydrophobic PVDF membrane technology combined with triple-layer glass fiber and polypropylene prefilter system resolves these challenges. Consequently, technical specifications including 5.8 psi bubble point, 100 µL holdup volume, and 32 ml flow rate deliver reliable clarification performance across demanding chemical environments while triple prefilter stages capture gross particulates extending operational lifetime.

Key PVDF Membrane Characteristics

• Hydrophobic Surface Chemistry - Requires alcohol pre-wetting, enabling superior performance with organic solvents, aggressive acids, and non-aqueous mobile phases
• Broad Solvent Resistance - Maintains compatibility across alcohols, ketones, hydrocarbons, acids, and bases, ensuring structural integrity throughout challenging applications
• 0.45 µm Particulate Retention - Delivers clarification performance, removing suspended particles and cellular debris, protecting analytical instrumentation from sample contamination
• Low Protein Binding Properties - Maintains concentration through minimal biomolecule adsorption, preserving sample integrity in pharmaceutical and biological testing
• Superior Chemical Durability - Resists membrane degradation across extreme pH conditions and concentrated solvent exposures, delivering consistent clarification reliability

Key Construction Characteristics

• 100 µL Controlled Holdup Design - Preserves samples through optimized dead volume, minimizing loss of valuable analytical specimens in standard processing applications
• Polypropylene Housing with 60°C Rating - Provides reliable performance and chemical stability throughout diverse solvent processing and autoclave sterilization protocols
• Dual Luer-Lok/Luer Slip Connection - Ensures secure attachment versatility, accommodating diverse syringe types and laboratory equipment configurations for leak-free operation
• Triple Prefilter System (GF+GF+PP) - Reduces processing time through progressive particulate capture, extending membrane lifetime, and maintaining 32 ml flow rates in high dirt-load samples

Built to support your critical organic solvent clarification workflows where high particulate loads and chemical resistance cannot compromise processing throughput or analytical precision. The triple prefilter system prevents membrane fouling while hydrophobic PVDF membrane withstands aggressive chemicals. Your laboratory achieves workflow efficiency with validated 0.45 µm clarification performance, exceptional chemical compatibility spanning acids and organic mobile phases, and triple-layer prefilter protection delivering 32 ml flow rates across pharmaceutical development, chromatography, and chemical analysis applications requiring both particulate management and solvent resistance.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

5.8psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

32ml

Holdup Volume

100μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

GF+GF+PP

Sterility

Nonsterile

Sterilization

Autoclave at 121°C for 30min/ gamma 25kGy

Volume Throughput (ml)

50ml

Wetability

Hydrophobic

• HPLC Mobile Phase Clarification - Removes particulates from organic and aqueous mobile phases, protecting column performance and system longevity
• Organic Solvent Sample Preparation - Clarifies aggressive chemical samples for chromatography, maintaining chemical stability and analytical accuracy
• Paint and Coating Analysis - Processes viscous samples with high particulate content for quality control testing, supporting manufacturing specifications
• Polymer Solution Filtration - Clarifies dissolved polymers, removing undissolved material, protecting analytical equipment, and ensuring characterization accuracy
• Environmental Extractant Processing - Filters solvent extracts containing particulates for contaminant analysis, maintaining sample integrity throughout testing
• Pharmaceutical Formulation Clarification - Removes particles from drug solutions in organic solvents, ensuring product quality without compromising formulation chemistry