Tisch
PVDF Syringe Filters w/ 3 Pre-Filters, 0.45 um, 25mm, Sterile, 100/Pk SKU: SF18310

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18310

Featuring polyvinylidene fluoride membrane technology with 0.45 µm pore size, sterile packaging, and a triple-layer prefilter system, these 25mm diameter filters deliver clarification performance for highly particulate pharmaceutical and environmental samples requiring extended membrane lifetime, contamination-free processing, and chemical resistance across organic solvent systems without bacterial retention specifications. This configuration enables reliable processing of challenging sample matrices through progressive particle capture across dual glass fiber and polypropylene stages that protect the primary filtration layer from premature clogging. Meanwhile, the design with 4.08 cm² filtration area and 100 µL holdup volume maximizes recovery of valuable pharmaceutical compounds while enabling rapid 32 ml/min flow rates for routine analytical workflows requiring efficient clarification of particulate-laden samples with sterile handling capabilities.

Key PVDF Membrane Characteristics

• Hydrophobic surface requires pre-wetting with alcohols or compatible organic solvents before aqueous processing, optimizing performance for organic pharmaceutical clarification
• 0.45 µm pore size removes particulates from analytical samples for chromatography workflows, protecting downstream instrumentation without providing sterile-grade filtration
• Exceptional chemical resistance, stable operation with aggressive organic solvents, including chlorinated compounds, ketones, esters, and aromatic hydrocarbons across workflows
• Low protein binding characteristics minimize adsorption during sample preparation, preserving biomolecule concentration in pharmaceutical analytical applications
• Sterile packaging eliminates initial contamination risks for sensitive analytical samples, supporting quality assurance requirements in pharmaceutical laboratories

Key Construction Characteristics

• 100 µL holdup volume minimizes loss of valuable pharmaceutical compounds and analytical standards, maximizing recovery for medium-volume clarification applications
• Polypropylene housing construction provides structural integrity to 87 psi maximum operating pressure, delivering reliable performance for pressurized filtration systems
• Dual Luer-Lok and Luer-Slip connections integrate seamlessly with standard laboratory syringes without adapters, streamlining workflow integration in pharmaceutical testing
• Triple-layer prefilter system with dual glass fiber and polypropylene stages with sterile packaging captures coarse particulates progressively, dramatically extending membrane lifetime

Pharmaceutical and environmental laboratories processing particulate-laden samples require clarification technology that combines extended membrane lifetime with chemical resistance and sterile handling. PVDF syringe filters deliver 0.45 µm clarification performance through triple-layer prefilter protection and aseptic packaging. Designed for your most demanding sample matrices, this membrane technology provides operational excellence through progressive particle capture for extended filter life, validated chemical stability, and sterile packaging for pharmaceutical testing, environmental analysis, and quality control applications requiring reliable particulate removal without bacterial retention capabilities.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

5.8psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

32ml

Holdup Volume

100μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

GF+GF+PP

Sterility

Sterile

Volume Throughput (ml)

50ml

Wetability

Hydrophobic

• HPLC Mobile Phase Clarification - Removes particles from organic chromatography solvents with extended filter life for high-particulate pharmaceutical samples
• Environmental Extract Processing - Clarifies soil and sediment extracts in organic solvents, requiring particulate removal in environmental monitoring programs
• Pharmaceutical QC Testing - Filters particulate-laden drug formulations and organic extracts for chromatographic analysis in quality control laboratories
• Viscous Sample Clarification - Processes challenging pharmaceutical samples requiring extended membrane lifetime with high dirt-loading capacity
• Organic Reagent Filtration - Clarifies chemical solutions and solvent mixtures with high particulate content in pharmaceutical manufacturing applications
• Industrial Sample Preparation - Filters viscous polymer solutions and resin formulations requiring contamination-free handling in materials science testing