Tisch
PTFE Syringe Filters, Hydrophilic, 0.1um, 25mm, Luer-Lok/Luer Slip, Sterile, 100/Pk SKU: SF18082

Polytetrafluoroethylene (PTFE) Syringe Filters - SF18082

Mycoplasma contamination in medium-volume biological samples creates critical bottlenecks in pharmaceutical development and biotechnology research, where absolute sterility cannot be compromised. Traditional approaches struggle to balance submicron particle removal with maintaining acceptable flow rates while preventing pre-sterilization delays that risk contamination. Advanced hydrophilic PTFE membrane technology at 0.1μm eliminates these processing obstacles through validated mycoplasma retention capabilities combined with ready-to-use sterile packaging. Technical specifications include 29psi bubble point validation ensuring complete 0.1μm retention, 25mm platform with 4.08cm² filtration area, and 100μL holdup volume optimization delivering 50ml throughput capacity for demanding sterile processing workflows requiring immediate deployment capabilities.

Key PTFE Membrane Characteristics

• Validated 0.1μm Mycoplasma Removal - Provides absolute retention of mycoplasma organisms and submicron contaminants with 29psi bubble point verification
• Hydrophilic Surface Engineering - Modified fluoropolymer technology eliminates pre-wetting procedures, enabling immediate aqueous sample processing
• Chemical Resistance Platform - Maintains compatibility with analytical solvents and reagents while providing documented incompatibility guidelines
• Protein Preservation Technology - Low-binding surface characteristics maintain concentration of therapeutic proteins and biologics throughout processing
• Engineered Membrane Depth - 80-140μm thickness provides structural stability while maintaining efficient 10ml flow rate characteristics

Key Construction Characteristics

• 100μL Optimized Holdup Volume - Preserves samples through minimal dead space design, maximizing recovery of valuable biological specimens
• Ready-to-Use Sterile Packaging - Individual sterile units eliminate pre-sterilization delays and reduce contamination risks in critical workflows
• 25mm Medium-Volume Platform - 4.08cm² effective area enables processing of medium to large sample volumes up to 50ml capacity
• Integrated Polypropylene Prefilter - Extends membrane operational life through particulate protection while maintaining processing efficiency

Engineered for your critical mycoplasma removal requirements, this hydrophilic PTFE system combines operational confidence through 87psi burst pressure ratings with validated submicron retention capabilities. Your laboratory achieves immediate sterile processing through ready-to-use packaging while maximizing sample recovery through 100μL optimized holdup design, ensuring reliable performance across demanding biotechnology applications and pharmaceutical development workflows requiring absolute mycoplasma-free assurance.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

87psi.

Connection Type

Luer-Lok/ Luer Slip

Construction

PP

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

10ml

Holdup Volume

100μL

Incompatibility

Bases, esters, ethers, ketones

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-140μm

Pack Count

100

Pore Size (µm)

0.1

Prefilter (Yes/No)

Yes

Prefilter Material

PP

Sterility

Sterile

Volume Throughput (ml)

50ml

Wetability

Hydrophilic

• Cell Culture Sterile Processing - Removes mycoplasma contamination from culture media and supplements while maintaining sterility standards
• Pharmaceutical Formulation Development - Filters biologics and drug candidates requiring absolute mycoplasma removal and immediate sterile processing
• Biotechnology Quality Control - Processes samples for sterility testing and mycoplasma detection in manufacturing quality assurance programs
• Clinical Research Sample Preparation - Sterilizes biological specimens and therapeutic candidates for downstream analytical testing procedures
• Vaccine Production Processing - Provides mycoplasma-free filtration for vaccine components and biological production intermediates
• Research Biologics Filtration - Sterilizes protein therapeutics and research-grade biologics without thermal degradation or concentration loss