MCE Designed for TOC Determinations, .45 um, Prerinsed, 125mm Diameter, 50/Pk SKU: SF181127

Mixed Cellulose Ester (MCE) Membrane Filters - SF181127

The Tisch SF181127 protects sensitive instrumentation and sample integrity by providing reliable particulate removal with minimal analyte adsorption or background interference. Underpinning this performance, precision-manufactured hydrophilic membrane with a verified 0.45 pore structure delivers consistent retention across the full operating range. In practice, consistent surface properties across the full membrane area support uniform particle capture and reliable results in gravimetric, microscopic, and culture-based analytical workflows.

Material Specifications

• Known for excellent wetting properties and high flow rates in aqueous filtration.
• Low tare weight and complete solubility in organic solvents make MCE the standard membrane for gravimetric particulate analysis where method specifications demand minimal blank correction.
• Bulk format reduces per-unit packaging waste and cost, appropriate for routine particulate removal and clarification where aseptic handling is not specified.
• Feature a uniform pore structure that provides consistent flow rates and high throughputs across the full range of standard pore size ratings.
• Naturally hydrophilic membrane construction ensures spontaneous wetting on contact with aqueous solutions, eliminating pre-treatment delays.

Transitioning from qualitative screening to quantitative gravimetric analysis requires a membrane with documented tare weight consistency, and the manufacturing tolerances above ensure that your blank values remain within acceptable limits. Specifically, naturally hydrophilic MCE wets immediately on contact with aqueous samples, eliminating pre-conditioning and letting you begin filtration as soon as the membrane is seated. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

≥21.8 psi (water, 25°C)

Color

White

Diameter

125mm

Extractables

Moderate

Filtration Area

122.72cm²

Flow Rate

≥27 mL/min/cm²

Grid (Yes/No)

No

Material

Mixed Cellulose Ester (MCE)

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-120um

Pack Count

50

pH Range

2-10pH

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclave, EtO, Gamma Irradiation

Support Material

PET

Weight

0.32

Wettability

Hydrophilic

• Gravimetric Analysis - Maintains structural integrity during filtration and drying, providing precise weight measurements of retained particulates.
• Microscopy mounting - Can be made transparent with immersion oil, allowing for direct light microscopy of retained particles on the surface.
• Biochemical Assays - High electrostatic properties effectively bind proteins and macromolecules, supporting various diagnostic and research assays.
• Bioburden Monitoring - Routine testing of pharmaceutical water loops to ensure bioburden levels remain within safe production specifications.
• Black Grid Analysis - Black membrane variants enhance contrast for light-colored colonies, reducing eye strain during manual plate counting.
• Chemotaxis Assays - Acts as a barrier in Boyden chambers, allowing cells to migrate through defined pores towards a chemoattractant source.