Pura Disc 25mm H-PTFE Syringe Filters 0.45um, Hydrophilic, 1000 Pk
Whatman SKU: 6774-2504

Whatman Puradisc Water-Wettable PTFE Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - 6774-2504

Whatman applies over a century of filtration media expertise, manufacturing under the quality standards that established its products as global laboratory references. Syringe filters give the analyst a single-use device for clarifying samples right at the bench. The hydrophilic PTFE membrane resists strong acids, alkalis, and organic solvents and handles both aqueous buffers and organic solvents. Polypropylene construction holds extractable contribution low for sensitive analyses while routing flow to minimize backpressure in service and stays inert across common laboratory solvents. When sterile or particle-free preparation matters at the bench, the syringe filter delivers it with minimal added handling.

Technical Specifications

• Absolute pore-size rating gives consistent retention across protocols
• Chemically inert to aggressive organic solvents, strong acids, and alkalis
• Universal compatibility across aqueous buffers and organic solvents
• Water-wettable surface wets directly with both aqueous and organic samples
• Low protein binding preserves dilute analytes for maximum recovery

Housing Specifications

• Reliable housing-to-membrane seal prevents bypass at rated pressure
• Optimized internal geometry minimizes backpressure in service
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Stable across the full aqueous pH range in routine sample work

Filtering buffers, reagents, and aqueous samples keeps your preparation moving and consistent. Consistent aqueous clarification keeps your sample preparation moving from the first sample of the day through the last. Send your application details to our technical service team and request a filtration product recommendation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

0.6 bar (9 psi) [IPA]

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Flow Rate

~30 (MeOH)

Holdup Volume

<100µl

Material

Hydrophilic Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

1000

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophobic

• Aerosol Sampling - The hydrophobic nature of PTFE allows for gas venting and air monitoring applications in harsh environments
• Organic Mobile Phases - Ideal for filtering 100% organic solvents in HPLC and GC workflows without any membrane degradation
• Aggressive Solvent Filtration - PTFE is chemically inert, making it the only choice for filtering strong acids and bases
• Cryogenic Fluids - Remains functional and integral even at extreme temperatures, protecting sensitive equipment from damage
• Environmental Monitoring - Ideal for removing particulates in water and wastewater analysis to ensure regulatory compliance
• Biological Fluid Analysis - Protects sensitive downstream instruments from removing particulates that can cause system failure