Pura Disc 25mm PVDF Syringe Filters, 0.2um, 50 Pk
Whatman SKU: 6746-2502

Whatman Puradisc PVDF Syringe Filters, 0.2 µm, 25 mm, 50/Pk - 6746-2502

Whatman's filtration expertise, refined across a century-plus of disciplined manufacturing, has made its name synonymous with laboratory-grade quality worldwide. A sterilizing-grade syringe filter carries manufacturer bacterial retention testing built into the design, giving analysts documented sterile-grade performance without repeating that testing in-house for the format. The surface modification reverses PVDF's natural affinity for protein adsorption while resisting HPLC mobile phases, alcohols, and mild hydrocarbons and loads aqueous mobile phases on first contact. The polypropylene housing maintains its geometry through sample runs up to 121°C while keeping sample purity intact through the filtration pass and stands firm against aqueous acids, bases, and alcohols during regular handling. The bench setup stays free of autoclave cycles and housing-maintenance steps once a single-use sterilizing-grade filter handles the preparation.

Technical Specifications

• Resistance to hydrolytic degradation exceeds that of nylon membranes
• Membrane structure maintains integrity from -35 to 160°C
• Bacterial challenge testing with Brevundimonas diminuta at 10 million CFU per cm2 confirms sterilizing grade
• Autoclave sterilization cycles leave pore structure and flow performance intact
• Hydrochloric, dilute nitric, and up to 90% sulfuric acid cause no attack

Housing Specifications

• Translucent housing wall allows visual confirmation of sample flow during filtration
• Resists stress cracking from aqueous salt and buffer solutions
• Minimal intrinsic autofluorescence from the polypropylene housing supports background-sensitive fluorescence-based assay work downstream.
• Plasticizer-free polyolefin construction keeps the fluid path clean

Clarify your routine aqueous samples in a single pass and cut down on juggling multiple filter types at the bench. Consistent aqueous clarification clears particulates without slowing your bench routine the same way every time you run it. Ask about a quality certificate, lot documentation, or a blanket-order quote for your filtration order at any time.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1.8 bar (26 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

50

Pore Size (µm)

0.2

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophobic

• Pre-Blot Sample Prep - Ensures ultra-low protein binding for maximum sample recovery ahead of sensitive immunodetection protocols and assays.
• QuEChERS Extract Prep - Removes co-extracted waxes and pigments from QuEChERS extracts, protecting GC-MS and LC-MS systems during pesticide testing.
• Mycotoxin Screening - Clarifies grain and food extracts ahead of HPLC analysis, supporting reliable detection of aflatoxins and other mycotoxins.
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily.
• Beverage QC - Clarifies wine, beer, and juice samples ahead of HPLC testing for organic acids, sugars, and preservatives.
• Capillary Electrophoresis Prep - Clarifies CE sample buffers and matrices, supporting stable electropherogram baselines for accurate results.