Pura Disc 25mm PVDF Syringe Filters, 0.45um, 200 Pk
Whatman SKU: 6747-2504

Whatman Puradisc PVDF Syringe Filters, 0.45 µm, 25 mm, 200/Pk - 6747-2504

Whatman's expertise in cellulose, glass fiber, and polymeric membrane production guides material selection and quality control. At the point of sample preparation, a syringe filter removes particulates before the sample reaches the instrument. The hydrophilic PVDF membrane keeps analyte adsorption low for clean recovery and wets aqueous and HPLC samples on contact. The PP housing sustains efficient flow on viscous samples while holding extractables low for sensitive analyses and resists degradation from routine sample matrices. When method reproducibility rests on consistent sample prep, syringe filtration holds that standard injection after injection.

Technical Specifications

• Hydrophilic surface wets aqueous and HPLC samples without pre-wetting
• Low extractables preserve a clean chromatographic baseline
• Absolute pore size rating gives consistent results across protocols
• Mechanically durable membrane holds integrity under filtration pressure
• Resists HPLC mobile phases, alcohols, and mild hydrocarbons

Housing Specifications

• Thermal-bonded construction keeps adhesives out of the fluid path
• Reliable housing-to-membrane seal prevents bypass at rated pressure
• Low extractable contribution protects sensitive downstream analyses
• Resists aqueous acids, bases, and alcohols in routine sample prep

Filtering every buffer before loading keeps your instrument running clean and uninterrupted. Upstream buffer clarification keeps avoidable particulates out of your flow path before they reach the column inlet or detector. Reach out to the Tisch Scientific team for application support, volume pricing, and technical assistance with your filtration product selection.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1.2 bar (17 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

200

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophobic

• Western Blotting - Optimized for use in preparing samples for downstream blotting techniques where purity is paramount
• HPLC Sample Prep - PVDF provides a great balance of chemical compatibility and low background noise for sensitive UV detection
• Clarification of Biologicals - Perfect for removing particulates from biological fluids without removing the target biomolecules
• Protein Analysis - Ultra-low protein binding ensures that your expensive protein samples are not lost to the filter matrix
• Particulate Removal - Designed for removing particulates, this filter aids in protecting analytical instruments across diverse sample types
• Analytical Sample Prep - Optimized to ensure data integrity by effectively removing particulates before instrumental analysis