Acro Disc Syringe Filters w/ Nylon Membrane - DMSO-Safe - 0.2um, 25mm, Sterile, 50/Pk
Pall SKU: 4433

Pall Acrodisc Nylon Syringe Filters, 0.2 µm, 25 mm, 50/Pk - 4433

Pall Corporation brings decades of fluid management expertise to laboratory-scale filtration challenges. Across analytical workflows, the syringe filter is where particulates leave the sample stream. Nylon withstands elevated differential pressures with high tensile strength while providing sterile-grade retention at sub-micron pore sizes and arrives factory sterile for immediate single-use workflows. Polypropylene construction maintains a low-dead-volume internal flow path while staying inert across common laboratory solvents and keeps the fluid path low in extractable contamination. When chromatographic methods demand particle-free injections, point-of-use syringe filtration clarifies the sample before it reaches the column.

Technical Specifications

• Gamma-sterilized in sealed packaging for immediate aseptic use
• Absolute pore size rating provides consistent results across filtration protocols
• High tensile strength for stability under elevated differential pressures
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• Alkaline-resistant across a broad range of aqueous buffers

Housing Specifications

• Low extractable contribution protects sensitive downstream analyses
• Tough polypropylene body tolerates repeated handling at the bench
• Rigid polypropylene body holds its shape under manual filtration pressure
• Inert polyolefin wall contributes minimal sample adsorption to the filtrate

Sample clarification before injection is the cheapest insurance your chromatography system has. Upstream sample clarification keeps your separations clean and reproducible from sample preparation through final injection. Start a live chat with our customer support technicians for quick answers to your compatibility, sizing, and sterility questions.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

42psi

Burst Pressure (psi)

90psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

75ml

Holdup Volume

< 125 µL

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

50

Pore Size (µm)

0.2

Sterility

Sterile

Wettability

Hydrophilic

• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from hydrophilic mobile phases
• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols
• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients
• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis